Which is a health information exchange network for securely sharing clinical information over the Internet nationwide, spanning all 50 states and is the largest health information exchange infrastructure in the United States?

The eHealth Exchange is recognized as a significant health information exchange network that facilitates the secure sharing of clinical information across the United States. It encompasses all 50 states, making it the largest health information exchange infrastructure in the country. This network operates like a collaborative system that connects various healthcare stakeholders, including hospitals, laboratories, and specialists, enabling them to share patient information in a timely and secure manner.

By utilizing the eHealth Exchange, healthcare providers can improve continuity of care by having access to comprehensive patient data, which can enhance treatment decisions and improve patient outcomes. The framework ensures that sensitive health information is protected while still allowing the necessary exchange of data to happen efficiently.

Other options such as RHIO (Regional Health Information Organization), esMD (Electronic Submission of Medical Documentation), and the I2 Initiative focus on various aspects of health information management but do not provide the same nationwide, extensive infrastructure for data exchange that the eHealth Exchange offers. Therefore, the eHealth Exchange stands out for its scale and purpose in facilitating nationwide clinical information sharing.